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Day 1
Introduction, instrumentation & Praticals
Day 2
Instrumentation practicals II + quality control
Day 3
Processing and analysing bioimage data
9:00 AM — 9:30 AM
Welcome & intro to the workshop
9:30 AM — 11:00 AM
Deconstructing a microscope and basic care

 

  • The compound microscope
  • Disassembly and reassembly of a compound microscope
  • Light paths & image formation
  • Essential care of an optical microscope and components

 

COFFEE BREAK
11:45 AM — 12:15 PM
Illumination and filters in light microscopy
  • Bright-field illumination techniques
  • Lasers and LEDs as sources for fluorescence illumination
  • Fluorescence filters, spectral filtering and assessing illumination quality
12:45 PM
Sponsor pitch
LUNCH
1:45 PM — 2:15 PM
Sponsors talks
2:15 PM — 3:00 PM
Image detectors & Digital images

 

  • Cameras vs point-detectors. Quantum efficiency and dynamic range. Signal vs backgroung vs noise  (& types of noise).
  • Detectors characteristics and limitations.
  • Bioimage digital formats & managing bioimage data. 

 

3:30 PM — 4:00 PM
Optical sectioning methods - inside the box & choosing the right tool

Topics addressed: 

  • CLSM
  • SDCM
  • 2P
  • Light-sheet
  • OPT
COFFEE BREAK
4:15 PM
Sponsors pitch
8:00 PM — 10:00 PM
Dinner (@ "A Quinta" near train station)
9:00 AM — 11:30 AM
Optimizing CSLM acquisition + Airyscan
COFFEE BREAK
11:15 AM — 12:30 PM
Non-diffraction-limited imaging & nanoscopy techniques (Round Table)

Some of the topics addressed:

  • TIRF, ISM, SIM, STORM etc...
12:00 PM
Advanced fluorescence techniques: F techniques & photomanipulation (Round Table)

Some of the topics addressed: 

  • FRAP, FLIP
  • Photoablation
  • FRET
Sponsor pitch
LUNCH
Sponsor pitch
2:00 PM — 3:00 PM
Special sample preparation (tissue clearing & expansion microscopy)

Do's and don'ts of tissue clearing and expansion microscopy. 

Tested protocols, and how to image cleared and expanded samples.

3:00 PM — 4:00 PM
Basic maintenance and QC in microscopy instrumentation
COFFEE BREAK
Sponsor pitch
Wine & cheese reception (at the canteen)
free night (perhaps drinks at the BeerHunter?
9:00 AM — 11:00 AM
The "right" BiAs tools for each project

Round table with experts in:

FIJI

QuPath

CellProfiler

Imaris

Python and AI

COFFEE BREAK
11:15 AM — 12:00 PM
Deconvolution with PPBI Huygens
12:00 PM — 1:00 PM
Imaris in PPBI - Beyound the basics
LUNCH
2:00 PM — 5:00 PM
Train the trainer & management (Round Table)
COFFEE BREAK
Conclusion...

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