The workshop is organized as a three-day event. Each day is dedicated to a specific topic and will comprise a set of lectures followed by hands-on sessions of data analysis.
Day 1 - June 6th (Tu)
From samples to data
Morning session (9am - 12pm)
• Hector Gallart-Ayala & Julijana Ivanisevic - From samples to data: intro, exp design, sample handling, storage and preparation, data acquisition & quality assessment. ~ 1.30 h
• Denise Medeiros Selegato - From Data to Metabolites: compound annotations based on the integration of mass spectral information. ~ 1.30 h
Lunch break & poster session
Afternoon session (2pm – 5pm)
• Serge Rudaz & Julien Boccard - From data to biologically relevant patterns: Theory behind principal component analysis & hands-on tutorial on how to use it for metabolomic data analysis. ~3h (1h lecture + 2h hands-on session)
Apero & poster session
Day 2 - June 7th(We)
Pathway and Metabolic Network Analysis
Morning session (9am - 12pm)
• Ludovic Cottret & Clément Frainay - Metabolic network analysis with MetExplore. ~ 3h (1h lecture + 2h hands-on session)
Lunch break and poster session
Afternoon session (2pm – 5pm)
• Tim Ebbels & Cécilia Wieder - Mapping metabolites into biochemically relevant context: Theory behind pathway analysis & hands-on tutorial on how to perform pathway analysis. ~ 3h (1h lecture + 2h hands-on session)
Social event - TBD
Dinner
Day 3 - June 8th (Th)
Metabolite Data-driven stories
Morning session (9am - 12pm)
• Andrew Quinn - How SCFA analysis contribute to deciphering the metabolic crosstalk between honeybees and their gut microbiota? ~ 45’
• Sammy Pontrelli - Using high throughput metabolomics to uncover metabolic crossfeeding networks in marine microbial communities. ~ 45
• Manuel Liebeke - Taking a Microscale Look at Host-Microbe Interactions: Visualizing Cells and Metabolites in One Picture. ~ 45’
• Jiayi Lan - Non-invasive metabolic monitoring via volatiles. ~ 45’
Afternoon session (2pm – 5pm)
• Anders Meibom - TBD ~ 45’
• Mojgan Masoodi - Lipidomics to evaluate the impact of microbiome on host lipid metabolism in relation to metabolic disorders. ~ 45’
• Mirko Trajkovski - Temperature and metabolic health: Integrating metagenomics with metabolomics in search of the mechanisms. ~ 45’
What happens during the workshop
The course will consist of general lectures, practical hands-on sessions, and research seminars. Lectures will cover the state of the art in specific areas of the field and will give the students a broad view of that area. Lecturers will also present their own research on these topics giving the students insight on how specific problems are currently addressed using various metabolomics approaches.
Additionally, each participant will present their own research or research ideas during a poster session. To this end, each participant is asked to bring a poster about their research work.
We will have 25 participants and at least 16 lecturers to ensure a good participants/lecturer ratio and promote a strong interaction between teachers and participants.
Specific Course Activities:
Daily lectures and hands-on practical sessions on the design of metabolomics experiments, data acquisition approaches, data annotation challenges, data analysis, visualization and interpretation
Research seminars on the most recent metabolomics approaches and their application to address biological problems in the context of microbe-host interactions.
Poster sessions for the participants to present and discuss their research and provide an opportunity to exchange with experts in the field of metabolomics/lipidomics/chemical ecology/mass spectrometry imagine.
Social activities: Lunch breaks at the local cafeteria, apero during poster session, and dinner on Wednesday evening.